6 EC
Semester 1, period 1
5254SUCN6Y
Owner | Master Chemistry (joint degree) |
Coordinator | dr. R.M. Williams |
Part of | Master Chemistry (joint degree), track Molecular Sciences, |
Supramolecular chemistry
The course lays down the basic principles of supramolecular chemistry: molecular self-assembly by using non-covalent interactions, such as hydrogen-bonding, hydrophobic forces, metal coordination and π-π interactions. Molecular self-organization, pre-organization, templating and self-organized growth are exemplified. Host-guest complexes that are made up of two or more parts and are held together through non-covalent interactions, which can reversibly bind and dissociate are also studied. A special topic in supramolecular chemistry is formed by mechanically interlocked molecular structures, such as rotaxanes and catenanes that are bound as a result of their topology. Supramolecular catalysis forms an important aspect of the course. Thermodynamic aspects as well as the importance of the molecular environment in supramolecular chemistry are discussed as well as the synthesis and characterization of artificial supramolecular assemblies.
Nanomaterials.
This part begins with an introduction to nanotechnology. Nanomaterials are composed of (molecular) units and have features on the 1-100 nm scale that determine their function, and behave different from the bulk. Examples of functional photo-active nanomaterials are discussed. The concepts in supramolecular chemistry for synthesis of supramolecular constructs are prevalent in nanotechnology and nano-science. Self-assembly is one of the options to make nano-structures. Quantum dots, nanoparticles and various applications of nanomaterials including medicine, catalysis and especially (organic) photovoltaïcs are discussed.
The final part of the nanomaterials part of this course concentrates on fast spectroscopy in supramolecular chemistry and (photovoltaic) nanomaterials. Various time-resolved techniques are exemplified in order to understand more about photoinduced processes, excited states in supramolecular systems, rates and mechanisms of different photochemical processes.
Limitations of photovoltaics are discussed. Several photovoltaic materials in which nano-structure plays a role are treated.
Lectures and tutorials. Presentations by the students.
Suggestions will be given but you can choose a scientific paper yourself to present during the course (we have to approve your choice at the beginning of/during the course). It should be about 'Supramolecular Chemistry' or about 'Nanomaterials'. We recommend 'Science' or 'Nature' papers. But, other journal are also possible.
Activity | Number of hours |
Hoorcollege | 26 |
Tentamen | 3 |
Zelfstudie | 139 |
This programme does not have requirements concerning attendance (TER part B).
Item and weight | Details |
Final grade | |
1 (100%) Tentamen |
The exam makes up 65% of the final grade, and contains 4 questions.
The assignment of the research proposal that has to be uploaded makes up 20%.
(in former years this was exam question 1).
The presentation at the symposium makes up 10%.
The assignments that have to be uploaded at the end of (zoom)-lecture days make up 5%.
The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl
Lectures Reek: Supramolecular Chemistry
Lecture 1
General introduction to supramolecular chemistry, bonding/interactions in supramolecular chemistry, thermodynamics of supramolecular assemblies, analytical methods
Literature: Chapter 1 and 2, 10.4, 10.7
Lecture 2
Complexation, equilibrium and basic thermodynamics;
A simple model to estimate binding strength (Hunter);
Experimental characterization of binding.
Literature references in slides and Chapter 3, Chapter 4, 10.4,
C. A. Hunter, Quantifying Intermolecular Interactions: Guidelines for the Molecular Recognition Toolbox, Angew. Chem. Int. Ed. 2004, 43, 5310-5324.
Lecture 3
Model validation;
Host-guest systems for ionic and neutral species;
Hydrogen-bond based assemblies & cooperativity
Literature references in slides and Chapter 6
A. Mulder, J. Huskens, D. N. Reinhoudt, Multivalency in supramolecular chemistry and nanofabrication, Org. Biomol. Chem., 2004, 2, 3409-3424.
Lecture 4
Larger self-assemblies based on hydrogen bonding
Hydrogen bonded capsules
Supramolecular polymers
Chapter 10.6, lecture slides and papers provided on canvas
Lecture 5
Coordination chemistry and organometallic chemistry as tool in supramolecular chemistry.
Metal organic cages (MOC
Metal based nanaospheres.
Chapter 9.5, lecture slides and papers provided on canvas
Lecture 6
Supramolecular catalysis
Chapter 6, lecture slides and papers provided on canvas
Lectures Williams: Nanomaterials
Lecture 1
Introduction to nanotechnology.
chapter 15 (page 900-937).
Connecting nanotechnology to Supramolecular chemistry
Chapter 1, (page 1-45);
Chapter 10 (page 591-697);
Chapter 13, page 837-839
Chapter 6, page 320-321
Lecture 2
Fast spectroscopy in Supramolecular Chemistry and Nanomaterials
Chapter 11.
and
https://www.researchgate.net/publication/225188430_Introduction_to_Electron_Transfer
or (same document from different source)
Lecture 3
Organic Solar Cells: photo-generation of free charges, molecular organization and fast spectroscopy
http://onlinelibrary.wiley.com/doi/10.1002/anie.200702506/abstract
and
http://pubs.rsc.org/is/content/articlehtml/2009/ee/b812502n
Lecture 4/6
to be announced
The schedule for this course is published on DataNose.