Course manual 2020/2021

Course content

Lectures in advanced signal transduction

Practical course in FoxO transcription factors
Bioinformatics course
Meet the expert technology workshops

Subjects the student will master at the end of the course:

What are the basic signal transduction pathways involved in neuronal maintenance and development?
How to incorporate current literature and technology about signal transduction into a relevant research question?
How to critically design a research strategy to investigate a signal transduction pathway in a neuronal system?

Study materials

Syllabus

Study material and information will be provided at the course and will consist of a selection of excellent scientific papers published in international high-impact journals.

Objectives

distinguish and interpret signal transduction routes in the brain.
criticize and evaluate scientific literature on signal transduction.
independently design and execute an experiment in a laboratory.
evaluate experimental results (from a self-designed experiment).
design, analyse and criticize an experiment (using bio-informatic tools).
interpret experimental results and present these in an oral presentation to a scientifically oriented public.
formulate a relevant research question about a neurological disease, using current literature and technology.
design an innovative and state-of-art research strategy.
to present a self designed research strategy, both in a written report and in an oral presentation, to a scientifically oriented public.

Teaching methods

Lecture
Seminar
Computer lab session/practical training
Presentation/symposium
Self-study
Working independently on e.g. a project or thesis
Supervision/feedback meeting

The courses will be both of theoretical and practical in nature. The student will attend lectures, perform experiments, critically evaluate literature, and give presentations covering the practical work and literature performed and discussed during the course. In addition an assignment covering all three courses will be completed.

Learning activities

Activity	Number of hours
Computerpracticum	4
Hoorcollege	26
Practicum	72
Presentatie	12
Tentamen	4
Werkcollege	4
Zelfstudie	46

Attendance

This programme does not have requirements concerning attendance (TER part B).

Assessment

Item and weight	Details
Final grade
50% Tentamen

Inspection of assessed work

Contact the course coordinator to make an appointment for inspection.

Assignments

Practical Training

Oral presentation

You will present your experimental results in an oral presentation.

Assignment

You will work on this assignment during the three courses. You should design a research strategy and write and orally present a proposal. You will work in pairs.

Fraud and plagiarism

The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl

Course structure

Weeknummer	Onderwerpen	Studiestof
1
2
3
4
5
6
7
8

Timetable

The schedule for this course is published on DataNose.

Additional information

A course in molecular biology and/or neurobiology is advised

The maximum number of students is 20.

Contact information

Coordinator

dr. L.P. van der Heide

Owner	Master Biomedical Sciences
Coordinator	dr. L.P. van der Heide
Part of	Master Biomedical Sciences, track Molecular Neuroscience,

Signal transduction pathways in neuronal systems