Course manual 2019/2020

Course content

Objectives: To acquire a physical understanding of the concepts of one- and two-dimensional NMR techniques and appreciate their essential role and application in the different fields of analytical chemistry.

Contents: A comprehensive overview of the physical basis of NMR spectroscopy followed by the general experimental aspects associated with obtaining and analyzing spectra. The analysis and interpretation of both 1D (1H, 13C, and selected heteronuclear) and 2D spectra of organic molecules will be emphasized.

Study materials

Literature

H. Günther, ‘NMR Spectroscopy: Basic Principles, Concepts and Applications in Chemistry’ Third Edition, Wiley-VCH.

Other

Handouts, literature articles.

Objectives

Acquire physical understanding of the concepts of one- and two-dimensional NMR techniques essential.
Understand role and application of NMR in the different fields of analytical chemistry.
Analyse and interpret both 1D (1H, 13C, and selected heteronuclear) and 2D spectra of organic molecules.

Teaching methods

Lecture
Seminar
Self-study
Computer lab session/practical training
Fieldwork/excursion

Learning activities

Activity	Number of hours
Lectures	28
Seminar/tutorials	12
Computer lab	4
Excursion	4
Self-study	100

Attendance

This programme does not have requirements concerning attendance (TER part B).

Assessment

Item and weight	Details
Final grade
0.5 (50%) Exam
0.3 (30%) Group presentations
0.1 (10%) Computational lab
0.1 (10%) Experimental lab

The exam covers all content covered during the lectures and tutorials.

The grade for the exam should be higher than 5.5.

Inspection of assessed work

Contact the course coordinator to make an appointment for inspection.

Fraud and plagiarism

The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl

Course structure

Weeknummer	Onderwerpen	Studiestof
1	Introduction; chemical shift; spin-spin coupling	Ch.1-3
2	Instrumentation; proton NMR	Ch. 4-5
3	High Res-NMR, Symmetry and chirality; computational NMR	Ch. 6-7
4	2D NMR	Ch. 9
5	13C NMR, experimental NMR lab	Ch. 11
6	Group presentation prep
7	Group presentations and question hour
8	Exam

Owner	Master Chemistry (joint degree)
Coordinator	dr. T.A. Hamlin
Part of	Master Chemistry (joint degree), track Analytical Sciences,

Analytical NMR spectroscopy