Supramolecular Chemistry and Nanomaterials

Course manual 2019/2020

Course content

Supramolecular chemistry
The course lays down the basic principles of supramolecular chemistry: molecular self-assembly by using non-covalent interactions, such as hydrogen-bonding, hydrophobic forces, metal coordination and π-π interactions. Molecular self-organization, pre-organization, templating and self-organized growth are exemplified. Host-guest complexes that are made up of two or more parts and are held together through non-covalent interactions, which can reversibly bind and dissociate are also studied. A special topic in supramolecular chemistry is formed by mechanically interlocked molecular structures, such as rotaxanes and catenanes that are bound as a result of their topology. Supramolecular catalysis forms an important aspect of the course. Thermodynamic aspects as well as the importance of the molecular environment in supramolecular chemistry are discussed as well as the synthesis and characterization of artificial supramolecular assemblies.

Nanomaterials.
This part begins with an introduction to nanotechnology. Nanomaterials are composed of (molecular) units and have features on the 1-100 nm scale that determine their function, and behave different from the bulk. Examples of functional nanomaterials are discussed. The concepts in supramolecular chemistry for synthesis of supramolecular constructs are prevalent in nanotechnology and nano-science. Self-assembly is one of the options to make nano-structures. Quantum dots, nanoparticles and various applications of nanomaterials including medicine, catalysis and especially (organic) photovoltaics are discussed. The final part of the course concentrates on fast spectroscopy in supramolecular chemistry and (photovoltaic)nanomaterials. Various time-resolved techniques are exemplified in order to understand more about photoinduced processes, excited states in supramolecular systems, rates and mechanisms of different photochemical processes. Limitations of photovoltaics are also discussed.

Study materials

Literature

• Jonathan W. Steed, Jerry L. Atwood, 'Supramolecular Chemistry', 2nd Edition; ISBN: 978-1-118-68150-3 Chapters 1, 2, 6, 9, 10, 11, 12, 15. The first four are introductory, the last four are the specialized topics. http://onlinelibrary.wiley.com/book/10.1002/9780470740880 (e-book available within UvA or VU domain.)
• C.A. Hunter, 'Quantifying molecular interactions: Guidelines for the molecular recognition toolbox', Angewandte Chemie, 43 5310-5324, 2004. http://dx.doi.org/10.1002/anie.200301739 (available within UvA or VU domain.)

Objectives

• use molecular building blocks to design functional (photo-active) supramolecular constructs and nano-structured materials by using the principles of Supramolecular Chemistry.
• describe the molecular basis of the formation and (photo)-functioning of supramolecular assemblies and nanomaterials.
• quantify molecular interactions by using the molecular recognition toolbox developed by Hunter (functional group interactions diagrams) with respect to Gibbs free energy change and complex formation constants.
• select a specific type of (time-resolved) spectroscopy to study interactions between different groups in supramolecular assemblies and photo-active nanomaterials and design experiments to quantify these (photoinduced) interactions.
• present clearly and concisely a (recent) scientific paper on supramolecular chemisty or on nanomaterials/nanoscience (to the fellow-students).
• use creativity with respect to developing new scientific concepts and scientific research topics.
• write an original research proposal describing new ideas and concepts that in principle could be the basis of a PhD research in the area of supramolecular chemistry or in the area of nanomaterials (this is in fact exam question 1; you can start working on it now!!). Answering this first exam question is mandatory!

Teaching methods

• Lecture
• Seminar
• Presentation/symposium

Lectures and tutorials. Presentations by the students.

Suggestions will be given but you can choose a scientific paper yourself to present during the course (we have to approve your choice at the beginning of/during the course). It should be about 'Supramolecular Chemistry' or about 'Nanomaterials'. We recommend 'Science' or 'Nature' papers. But, other journal are also possible.

Learning activities

Attendance

The programme does not have requirements concerning attendance (OER-B).

Assessment

The exam makes up 90% of the final grade. The presentation at the symposium makes up the 10%.

Fraud and plagiarism

The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl

Course structure

Timetable

The schedule for this course is published on DataNose.

Contact information

Coordinator

• dr. R.M. Williams

Staff

• dr. Tiddo Mooibroek
• prof. dr. Joost Reek