Separation Sciences

6 EC

Semester 1, period 1

52548SES6Y

Owner Master Chemistry (joint degree)
Coordinator dr. W.T. Kok
Part of Master Chemistry (joint degree), track Analytical Sciences, year 1

Course manual 2017/2018

Course content

The topics discussed comprise the fundamentals, theory and practice of gas chromatography, the various modes of liquid chromatography, capillary-based electrophoretic approaches as well as the hyphenation of the various separation systems with mass spectrometry and other sensitive and selective detection devices.  Attention will be given to new developments and trends(new stationary phase formats, UHPLC, 2-dimensional systems, separation methods for (bio-)macromolecules).

As part of the course students will present a scientific paper on separations.

 

Study materials

Literature

  • will be available on Blackboard (reviews, notes)

Other

  • handouts

Objectives

At the end of the course students will be able to:

  • explain the fundamentals of different separation methods;
  • use different performance parameters to compare methods;
  • predict the effects of experimental parameters on the performance of methods and use this for optimizaton;
  • translate experimental data into chemical information;
  • propose suitable methods for various applications;
  • read, summarize and present relevant scientific papers

Teaching methods

  • Lecture
  • Seminar
  • Presentation/symposium

Learning activities

Activity

Number of hours

Lectures/seminars

36

Presentation incl. preparation

12

Zelfstudie

120

 

Attendance

The programme does not have requirements concerning attendance (OER-B).

Assessment

Item and weight Details Remarks

Final grade

0.8 (44%)

Tentamen 1

0.8 (44%)

Hertentamen

0.2 (11%)

Presentation

Best ofFinal score is calculated from Written Exam score (max.10) and BonusPoints (max.2) as: F = WE + PB - 0.1*WE*BP

Inspection of assessed work

Contact the course coordinator to make an appointment for inspection.

Fraud and plagiarism

The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl

Course structure

wk day date room lecturer topic    
               
36 Tue 5-Sep WN-M143 + M639 WK Introduction; dispersion
  Fri 8-Sep HG-02A24+WN-S623 HL Phase systems 1  
37 Tue 12-Sep WN-M143 + M639 HL Phase systems 2  
  Fri 15-Sep HG-02A24+WN-S623 WK Detectors in LC  
38 Tue 19-Sep WN-M143 + M639 WK Chromatographic signals and data processing
  Fri 22-Sep HG-02A24+WN-S623 HL Gradient systems  
39 Tue 26-Sep WN-M143 + M639 WK Electrophoretic separations
  Fri 29-Sep HG-02A24+WN-S623 HL Hyphenated systems (LC-MS, ...)
40 Tue 3-Oct WN-M143 + M639 WK Separation of macromolecules (SEC,HDC,FFF)
  Fri 6-Oct HG-02A24+WN-S623 PS Gas Chromatography 1
41 Tue 10-Oct WN-M623 + M639 PS Gas Chromatography 2
  Fri 13-Oct HG-02A24+WN-S623 PS GCxGC    
42 Tue 17-Oct WN-M143 + M639 --- Student presentations
  Fri 20-Oct HG-02A24+WN-S623 --- Student presentations
               
43 Tue 24-Oct various -- Exam (15:15-18:00h)

Timetable

The schedule for this course is published on DataNose.

Contact information

Coordinator

  • dr. W.T. Kok

Staff

  • dr. H. Lingeman

Staff

  • dr. H. Lingeman