6 EC
Semester 1, period 2
5234GACD6Y
The Experimental Internal Medicine track is unique because it is fully taught at an academic hospital, the Academic Medical Center, by experts in the different fields covered during the course. When choosing this track you will be exposed to a broad range of basic and applied clinical research, and have the opportunity to meet leading basic and clinical researchers working on diverse topics that are important for human health. This course also serves as an excellent platform to explore internships and careers in biomedical research.
This four week course is divided in two periods. The first two weeks of the course focus on gastroenterology-related topics, while the second half of the course focuses on cardiovascular-related issues.
The liver and intestine are our largest organs, but it is their complexity and importance for many physiological processes that makes them so fascinating. Liver and intestinal diseases are an enormous burden on society, and importantly, the etiology of many gastrointestinal diseases is still unknown. In the first half of this master-level course, students are taken on a journey through the normal function of the intestine and liver. You will not only learn how our digestive system functions under normal conditions but also what happens when inflammatory or metabolic diseases affect proper functioning of these key organs.
The cardiovascular system supplies both the early embryo and the adult with blood containing the nutrients and oxygen vital to development and survival. Although essentially just a muscular pump with a system of tubes, the complexity and diversity of cardiac disorders does not reflect its apparent simplicity of function. Similarly, the vasculature is not merely a collection of tubes through which blood flows; Vascular dysfunction represents an early and critical step in many human diseases, most notably coronary artery disease. Cardiovascular diseases comprise a large biomedical area; Cardiac pump function and heart failure, cardiac excitation and sudden cardiac death, atherosclerosis and ensuing ischemic heart disease.
In this course you will receive up to date state scientific insights into these biomedical areas, the clinical expression of diseases therein, and the experimental techniques, and animal models used to unravel the biological underpinnings of normal and diseased states.
Topics that will be covered in this course are broad and range from genome wide association studies, stem cell biology, metabolism, immunology, electrophysiology to clinical treatment and surgery.
scientific articles
After the course, the student should be able to:
|
Activity |
Number of hours |
|
Practical lab work |
34 |
|
Presentation |
3 |
|
Exam |
3 |
|
Seminar |
49.25 |
|
Self study |
78.75 |
|
Total 6 EC x 28 h |
168 |
The programme does not have requirements concerning attendance (OER-B).
Additional requirements for this course:
Additional requirements for this course:
All course elements are mandatory. Notice of absence is required from the coordinators.
| Item and weight | Details | Remarks |
|
Final grade | ||
|
1 (25%) Abstract (individual) | ||
|
1 (25%) Exam | Although this is not a pass or fail exam, a low grade may reflect poorly on the student when applying for an internship. | |
|
1 (25%) Presentation lab assignment (duo) | ||
|
1 (25%) Presentation proposal (individual mark) |
The exam is of a multiple choice format based on the cardiovascular portion only. Questions are set by each individual lecturer. The questions are based on the lecturer's whole presentation, and may also represent elements learned during practical work. The exam is not digital and requires only a pen to mark answers. There is no strict policy of pass or fail for this individual component, though students should be aware that low grades may reflect poorly when applying for an internship.
Contact your supervisor to make an appointment for inspection.
For personal feedback the student can contact the individual course coordinators: for the first two weeks Jurgen Seppen (j.seppen@amc.uva.nl), the third week Noam Zelcer (n.zelcer@amc.uva.nl) and the forth week Phil Barnett (p.barnett@amc.uva.nl). For overall support the track coordinator is available: Anje te Velde (a.a.tevelde@amc.uva.nl).
Includes an electronic exam. This will not be assessed.
Introduction in lab work with several PhD students.
Writing an abstract, related to the topic of the mini lab projects.
Presentation of the mini lab projects.
In groups, a proposal will be designed and presented of the use of a new therapeutic target.
will not be assessed
will not be assessed
Cardiac section only. 30 MC questions covering topics of heart development and function only. Graded.
Onderstaande opdrachten komen aan bod in deze cursus:
Dit vak hanteert de algemene ‘Fraude- en plagiaatregeling’ van de UvA. Onder plagiaat of fraude wordt verstaan het overschrijven van het werk van een medestudent dan wel het kopiëren van wetenschappelijke bronnen (uit bijvoorbeeld boeken en tijdschriften en van het Internet) zonder daarbij de bron te vermelden. Uiteraard is plagiaat verboden. Hier wordt nauwkeurig op gecontroleerd en streng tegen opgetreden. Bij verdenking van plagiaat wordt de examencommissie van de opleiding ingeschakeld. Wanneer de examencommissie overtuigd is dat er plagiaat gepleegd is dan kan dit maximaal leiden tot een uitsluiting van al het onderwijs van de opleiding voor een heel kalenderjaar. Zie voor meer
informatie over het fraude- en plagiaatreglement van de Universiteit van Amsterdam.www.uva.nl/plagiaat
| Weeknummer | Onderwerpen | Studiestof |
| 1Gastroenterology and Liver research | various topics, practicum anatomy of the mouse, 4 afternoons working in the lab together with a PhD student, writing an abstract and presentation of the lab work | |
| 2Gastroenterology and Liver research | 3 afternoons working in the lab together with a PhD student, writing an abstract and presentation of the lab work | |
| 3Cardiovascular research | lectures on cardiovascular diseases, designing and presenting a proposal | |
| 4Cardiovascular research | lectures on cardiovascular diseases, practicum anatomy of the heart and ECG, exam covering the content of week 4 | tba |
| 5 | ||
| 6 | ||
| 7 | ||
| 8 |
Location: Academic Medical Center