Course manual 2016/2017
Course content
This course will start with a general overview the various types of
models used to describe biomedical processes by parametric and
non-parametric models using linear and non linear (differential)
equations. Basic knowledge of vector and matrix calculations and
differential equations is required but will be refreshed.
During the course, attention will be paid to viscoelastic models,
spectral analysis, compartment models, geometric modelling used in image
analysis and models to describe molecular structures and their dynamic
behaviour.
Examples will concentrate on cardiovascular function: linear and
nonlinear
viscoelastic models of pressure volume relations, compartment models of
the interaction between contractile proteins to simulate force and
pressure development and a description of an ion pump for instance to
import Ca-ions into the cell during an action potential.
The introductory lectures will be combined and followed by practical
courses in which, through exercises, experience will be gained of
MatLab and Mathematica (4th generation computer languages). Finally
students will be offered a choice of 1 out of 5 modelling problems to
be solved in small groups, guided by a supervisor. At
the end of the course each group will present and discuss their work
with all participants and supervisors of the course.
Study materials
Syllabus
Software
Objectives
To gain knowledge of the most important theoretical and practical
concepts in modelling and simulation of biomedical processes at
different scales, ranging from macroscopic organ function, cellular
function down to biochemical interactions and signaling pathways within
cells.
To gain experience with and to apply MatLab and Mathematica to acquire,
analyse and evaluate biomedical signals and to model and simulate
biomedical processes.
Teaching methods
- Lecture
- Computer lab session/practical training
- Presentation/symposium
Learning activities
Activity | Hours |
Hoorcollege | 27.25 |
Practicum | 15.25 |
Tentamen | 2.75 |
Self study | 122.75 |
Total | 168 | (6 EC x 28 uur) |
Attendance
Requirements concerning attendance (OER-B).
In addition to, or instead of, classes in the form of lectures, the elements of the master’s examination programme often include a practical component as defined in article 1.2 of part A. The course catalogue contains information on the types of classes in each part of the programme. Attendance during practical components is mandatory.
Assessment
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written report on the final assignment
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Inspection of assessed work
via email
Fraud and plagiarism
The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl
Course structure
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Coordinator