6 EC
Semester 1, period 2
5234GACD6Y
| Owner | Master Biomedical Sciences |
| Coordinator | dr. Anje te Velde |
| Part of | Master Biomedical Sciences, track Experimental Internal Medicine, |
The Experimental Internal Medicine track is unique because it is fully taught at an academic hospital, the Academic Medical Center, by experts in the different fields covered during the course. When choosing this track you will be exposed to a broad range of basic and applied clinical research, and have the opportunity to meet leading basic and clinical researchers working on diverse topics that are important for human health. This course also serves as an excellent platform to explore internships and careers in biomedical research.
The main goal of the course is to provide the students with a broad overview of the research that is done in the AMC in the respective themes dealt with in the course.
This four week course is divided in two periods. The first two weeks of the course focus on gastroenterology-related topics, while the second half of the course focuses on cardiovascular- and metabolism related issues and personalized medicine.
The liver and intestine are our largest organs, but it is their complexity and importance for many physiological processes that makes them so fascinating. Liver and intestinal diseases are an enormous burden on society, and importantly, the etiology of many gastrointestinal diseases is still unknown. In the first half of this master-level course, students are taken on a journey through the normal function of the intestine and liver. You will not only learn how our digestive system functions under normal conditions but also what happens when inflammatory or metabolic diseases affect proper functioning of these key organs.
The 3rd week of the course focuses on coronary artery disease, which is a primary cause of mortality and morbidity. This disease is associated with disturbed lipid metabolism as well as involvement of a low-grade inflammatory disease. During this week these processes will be presented, alongside the different cell types involved, and the modern methods that are used to study development of coronary artery disease. We will focus on understanding how lipid metabolism and inflammation are normally controlled in vascular and immune cells and outline how deregulation of this may lead to development of coronary artery disease.
The 4th week will be used to discuss several aspects of personalized medicine. Personalized medicine is an emerging practice of medicine that uses an individual's genetic profile to guide decisions made in regard to the prevention, diagnosis, and treatment of disease.
In this course you will receive up to date state scientific insights into these biomedical areas, the clinical expression of diseases therein, and the experimental techniques, and animal models used to unravel the biological underpinnings of normal and diseased states.
Topics that will be covered in this course are broad and range from genome wide association studies, stem cell biology, metabolism, immunology to clinical treatment and surgery.
scientific articles
|
Activity |
Number of hours |
|
Practical lab work |
34 |
|
Presentation |
6 |
|
|
|
|
Seminar |
49.25 |
|
Self study |
78.75 |
|
Total 6 EC x 28 h |
168 |
Requirements of the programme concerning attendance (OER-B):
Additional requirements for this course:
All course elements are mandatory. Absence needs to be coordinated with the course coordinator.
If the student misses a lecture the student must make a short summary (1/2 A4) of the missed lecture, provided the ppt of the lecture is available. This summary must be send to the coordinator within a week after the missed lecture.
| Item and weight | Details |
|
Final grade |
The four different weeks will be graded and the final grade will be an average of this four grades.
Contact your supervisor to make an appointment for inspection.
For personal feedback the student can contact the individual course coordinators: for the first two weeks Anje te Velde (a.a.tevelde@amc.uva.nl), the third week Noam Zelcer (n.zelcer@amc.uva.nl) and the fourth week tba. For overall support the track coordinator is available: Anje te Velde (a.a.tevelde@amc.uva.nl).
Includes an electronic exam. This will not be assessed.
Introduction in lab work with several PhD students.
Writing an abstract, related to the topic of the mini lab projects.
Presentation of the subject of a PhD student in a movie format.
In groups, a proposal will be designed and presented of the use of a new therapeutic target.
tba
The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl
| Weeknummer | Onderwerpen | Studiestof |
| 1Gastroenterology and Liver research | various topics, practicum anatomy of the mouse | |
| 2Gastroenterology and Liver research | 7 afternoons generating a movie explaining the work of a PhD student in the Tytgat Laboratory, writing an abstract and presentation of movie. | |
| 3Cardiovascular research | lectures on cardiovascular diseases, designing and presenting a proposal | |
| 4Personalized Medicine | lectures on personalized medicine and assessment | |
| 5 | ||
| 6 | ||
| 7 | ||
| 8 |
Location: Academic Medical Center