Advanced Cognitive Neurobiology and Clinical Neurophysiology

Course manual 2022/2023

Course content

• Neurophysiology basics & techniques: electrophysiology (intracellular recordings; single, multi-unit, and population extracellular recordings), cellular imaging (two-photon), neurophysiology (population coding, brain rhythms, place fields), optogenetics
• Clinical neurophysiology: neuroimaging, nuclear medicine, neurology
• Advanced cognitive neurobiology: consciousness and perception, multisensory integration, oscillatory networks, human invasive electrophysiology
• Additional clinical lectures

Study materials

Literature

• Kandel, E.R. et al., Principles of Neural Science, Fifth Edition, McGraw-Hill

Other

• Lecturers will provide most of the study materials.

Objectives

• Explain in brain systems function, neural mechanisms of cognition and cognition-related brain disorders
• Describe and use neural techniques, mainly to measure and manipulate neural activity directly and with high spatio-temporal resolution
• Apply methodologies for the quantification of neural data & statistics
• Critically evaluate results and interpret neural data
• Interpret specialized neuroscientific literature
• Defend their answers, results and opinions in discussion/debating sessions

Teaching methods

• Lectures on Neurophysiology basics & techniques
• Home work assignments & return sessions
• Anatomy practicals (human & animal)
• Course part @ AMC: lectures and practicals on clinical neurophysiology
  
• Lectures on Advanced Cognitive Neurobiology
• Additional Clin. Neurophysiology lectures
• Workshops @ FNWI
  

• Lectures on Neurophysiology basics & techniques
• Home work assignments & return sessions
• Anatomy practicals (human & animal)
• Course part @ AMC: lectures and practicals on clinical neurophysiology
  
• Lectures on Advanced Cognitive Neurobiology
• Additional Clin. Neurophysiology lectures
• Workshops @ FNWI
  

Learning activities

Attendance

Requirements of the programme concerning attendance (OER-B):

1. Attendance during practical components exercises is mandatory.

Additional requirements for this course:

Students are required to participate in workgroups (a.k.a. "return sessions") and all practical activities (workshops, anatomy practicals, ...)

Assessment

Inspection of assessed work

The manner of inspection will be communicated via the digitial learning environment.

Fraud and plagiarism

The 'Regulations governing fraud and plagiarism for UvA students' applies to this course. This will be monitored carefully. Upon suspicion of fraud or plagiarism the Examinations Board of the programme will be informed. For the 'Regulations governing fraud and plagiarism for UvA students' see: www.student.uva.nl

Course structure

Timetable

The schedule for this course is published on DataNose.

Additional information

Prerequisites: Basic neurophysiology

The maximum number of students is 25. Admission to the course will depend on the capacity, the total number of applications, the date of registration and background of the individual student. If the number of applications exceeds the capacity of the course, student may have to be selected and priority will be given, in the following order:

• first-year students of the track Cognitive Neurobiology and Clinical Neurophysiology
• second-year students of the track Cognitive Neurobiology and Clinical Neurophysiology
• master students of the tracks Psychopharmacology & Pathophysiology or Basic and Applied Neuroscience
• master students of other programs

Contact information

Coordinator

• dr. Jorge Mejias